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Toplam kayıt 16, listelenen: 1-10
MDeePred: novel multi-channel protein featurization for deep learning-based binding affinity prediction in drug discovery
(Oxford University Press, 2021)
Motivation: Identification of interactions between bioactive small molecules and target proteins is crucial for novel drug discovery, drug repurposing and uncovering off-target effects. Due to the tremendous size of the ...
Carbon footprint forecasting using time series data mining methods: the case of Turkey
(Springer, 2021)
In the globalizing world, many factors such as rapidly increasing population, production and consumption habits, and economic growth cause climate changes. The carbon footprint is a measure of CO2 emissions released into ...
Modulation of Charge Transport at Grain Boundaries in SrTiO3: Toward a High Thermoelectric Power Factor at Room Temperature
(American Chemical Society, 2021)
Modulation of the grain boundary properties in thermoelectric materials that have thermally activated electrical conductivity is crucial in order to achieve high performance at low temperatures. In this work, we show ...
Fluorene/fluorenone carboxamide derivatives as selective light-up fluorophores for c-myc G-quadruplex
(Elsevier, 2021)
The development of fluorescent dyes capable of selective recognition of G-quadruplexes is essential for studying its localization and biological functions. However, considering the G-quadruplex topologies may vary ...
A novel electrochemical lung cancer biomarker cytokeratin 19 fragment antigen 21-1 immunosensor based on Si3N4/MoS2incorporated MWCNTs and core-shell type magnetic nanoparticles
(Royal Society of Chemistry, 2021)
Lung cancer is one of deadliest and most life threatening cancer types. Cytokeratin 19 fragment antigen 21-1 (CYFRA 21-1) is a significant biomarker for the diagnosis of non-small cell lung cancer (NSCLC). Due to these ...
Marine Algae Incorporated Polylactide Acid Patch: Novel Candidate for Targeting Osteosarcoma Cells without Impairing the Osteoblastic Proliferation
(MDPI, 2021)
Biodegradable collagen-based materials have been preferred as scaffolds and grafts for diverse clinical applications in density and orthopedy. Besides the advantages of using such bio-originated materials, the use of ...
Transcriptomic analysis of nonylphenol effect on Saccharomyces cerevisiae
(PeerJ Inc., 2021)
Nonylphenol (NP) is a bioaccumulative environmental estrogen that is widely used as a nonionic surfactant. We have previously examined short-term effects of NP on yeast cells using microarray technology. In the present ...
Initiated Chemical Vapor Deposition (iCVD) Functionalized Polylactic Acid-Marine Algae Composite Patch for Bone Tissue Engineering
(MDPI, 2021)
The current study aimed to describe the fabrication of a composite patch by incorporating marine algae powders (MAPs) into poly-lactic acid (PLA) for bone tissue engineering. The prepared composite patch was functionalized ...
In silico and in vitro assessment of androgen receptor antagonists
(Elsevier, 2021)
There is a growing concern for male reproductive health as studies suggest that there is a sharp increase in prostate cancer and other fertility related problems. Apart from lifestyle, pollutants are also known to negatively ...
Cryoprotective Effect of Vitamin E Supplementation of Different Extenders on Quality and Fertilizing Ability of Frozen-Thawed Brown Trout Sperm
(Mary Ann Liebert Inc., 2021)
Vitamin E is one of the most powerful antioxidants for prevention of cell damage resulting from cryopreservation, but its efficacy for cryopreserving brown trout sperm is still unclear. In this work, the protective effect ...