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MDeePred: novel multi-channel protein featurization for deep learning-based binding affinity prediction in drug discovery
(Oxford University Press, 2021)
Motivation: Identification of interactions between bioactive small molecules and target proteins is crucial for novel drug discovery, drug repurposing and uncovering off-target effects. Due to the tremendous size of the ...
Fluorene/fluorenone carboxamide derivatives as selective light-up fluorophores for c-myc G-quadruplex
(Elsevier, 2021)
The development of fluorescent dyes capable of selective recognition of G-quadruplexes is essential for studying its localization and biological functions. However, considering the G-quadruplex topologies may vary ...
A novel electrochemical lung cancer biomarker cytokeratin 19 fragment antigen 21-1 immunosensor based on Si3N4/MoS2incorporated MWCNTs and core-shell type magnetic nanoparticles
(Royal Society of Chemistry, 2021)
Lung cancer is one of deadliest and most life threatening cancer types. Cytokeratin 19 fragment antigen 21-1 (CYFRA 21-1) is a significant biomarker for the diagnosis of non-small cell lung cancer (NSCLC). Due to these ...
Cryoprotective Effect of Vitamin E Supplementation of Different Extenders on Quality and Fertilizing Ability of Frozen-Thawed Brown Trout Sperm
(Mary Ann Liebert Inc., 2021)
Vitamin E is one of the most powerful antioxidants for prevention of cell damage resulting from cryopreservation, but its efficacy for cryopreserving brown trout sperm is still unclear. In this work, the protective effect ...
Characterization of thermoluminescence kinetic parameters of beta irradiated B doped Ca5(PO4)3OH powder obtained from eggshell
(Elsevier, 2021)
In this study, we have synthesized B doped Ca5(PO4)3OH (HAP) by a sonication chemical method. The thermoluminescence (TL) properties of the family of synthesized samples (B doped Ca5(PO4)3OH (HAP) were investigated using ...