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dc.contributor.authorYalçın, Ergin
dc.date.accessioned2022-01-12T06:21:51Z
dc.date.available2022-01-12T06:21:51Z
dc.date.issued2021en_US
dc.identifier.citationYalçın, E. (2021). Diastereomeric Separation of a Novel Chalcone Derivative by Chiral HPLC. Adıyaman Üniversitesi Fen Bilimleri Dergisi. 11(1), 205-214. https://doi.org/10.37094/adyujsci.936678en_US
dc.identifier.urihttps://doi.org/10.37094/adyujsci.936678
dc.identifier.urihttps://hdl.handle.net/20.500.12508/2102
dc.description.abstractIn this study, a facile and versatile procedure for the synthesis of a chalcone derivate that a functionalized (E,Z)-2-(4-aminobenzylidene)acenaphthylen-1(2H)-one, 4 was synthesized and also characterized by using FT-IR, NMR and MS. A new HPLC method for the separation of its diastereomers was developed by using a chiral column that contains the amylose tris(3,5- dimethylphenylcarbamate) as a chiral selector since it is effective, reproducible and can be used for preparative purposes. High percentage recovery claims that the presented method was not affected by the impurities in the biological media. RSD% values for the repeatability studies suggest that the optimized method was highly precise and reproducible which is very important for these promising advances, chalcone-based science is expected to be applied in drug discovery.en_US
dc.language.isoengen_US
dc.publisherAdıyaman Üniversitesi Fen Bilimleri Dergisien_US
dc.relation.isversionof10.37094/adyujsci.936678en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectChalconeen_US
dc.subjectDiastereomeric separationen_US
dc.subjectAcenaphtenoneen_US
dc.subjectChiral columnen_US
dc.subjectHPLCen_US
dc.titleDiastereomeric Separation of a Novel Chalcone Derivative by Chiral HPLCen_US
dc.title.alternativeKiral HPLC ile Yeni Bir Kalkon Bileşiğinin Diastereomerik Ayrılmasıen_US
dc.typearticleen_US
dc.relation.journalAdıyaman Üniversitesi Fen Bilimleri Dergisien_US
dc.contributor.departmentMühendislik ve Doğa Bilimleri Fakültesi -- Mühendislik Temel Bilimleri Bölümüen_US
dc.identifier.volume11en_US
dc.identifier.issue1en_US
dc.identifier.startpage205en_US
dc.identifier.endpage214en_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.contributor.isteauthorYalçın, Ergin
dc.relation.indexTR-Dizinen_US


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