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The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens
(Bmc, 2019)
Background The Critical Assessment of Functional Annotation (CAFA) is an ongoing, global, community-driven effort to evaluate and improve the computational annotation of protein function. Results Here, we report on the ...
Assessment of heavy metal pollution of seston from freshwater resources poured into the Northeast Mediterranean region
(Springer, 2018)
This study was carried out to determine the accumulation levels of heavy metals (Zn, Cd, Pb, Cu, Fe, Cr) in seston to three different freshwater resources poured into the Iskenderun Bay. Seasonal averages of physicochemical ...
Heavy metal accumulation in rosemary leaves and stems exposed to traffic-related pollution near Adana-Iskenderun Highway (Hatay, Turkey)
(Springer, 2019)
Pollution has become a problem on a global scale and poses a significant risk in terms of human health and natural ecosystems. Generally, the biggest sources of pollution are municipal and industrial facilities. However, ...
Nonsteroidal anti-inflammatory drugs (NSAIDs) cause male-biased sex differentiation in zebrafish
(Elsevier, 2020)
Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used pharmaceuticals to treat pain, fever and inflammation. NSAIDs are also known to have many side effects including adverse effects on reproduction in both humans ...
The food preservative ethoxyquin impairs zebrafish development, behavior and alters gene expression profile
(Pergamon-Elsevier Science Ltd, 2020)
In the present study, we investigated the detrimental effects of ethoxyquin (EQ) on zebrafish embryonic development using different endpoints including lethality, malformations, locomotion and gene expression. EQ is primarily ...
Isoflurane versus sevoflurane for early brain injury and expression of sphingosine kinase 1 after experimental subarachnoid hemorrhage
(Elsevier Ireland, 2020)
The first step to treat aneurysmal subarachnoid hemorrhage (SAH) is aneurysmal obliteration under general anesthesia but not treat the SAH itself and the secondary effects. However, the identification of anesthetics with ...
Transcriptomic analysis of nonylphenol effect on Saccharomyces cerevisiae
(PeerJ Inc., 2021)
Nonylphenol (NP) is a bioaccumulative environmental estrogen that is widely used as a nonionic surfactant. We have previously examined short-term effects of NP on yeast cells using microarray technology. In the present ...
Heavy metal bioaccumulation, oxidative stress and genotoxicity in African catfishClarias gariepinusfrom Orontes river
(Springer, 2020)
One of the major problems affecting the ecosystem health is the exposure of heavy metals due to anthropogenic activities. These exposures may induce toxiogenetic damage and carcinogenesis in aquatic organism. DNA damage ...
CROssBAR: comprehensive resource of biomedical relations with knowledge graph representations
(Oxford Academic, 2021)
Systemic analysis of available large-scale biological/biomedical data is critical for studying biological mechanisms, and developing novel and effective treatment approaches against diseases. However, different layers of ...
The brominated flame retardants TBECH and DPTE alter prostate growth, histology and gene expression patterns in the mouse
(Elsevier, 2021)
The brominated flame retardants (BFRs), 1,2-dibromo-4-(1,2 dibromoethyl)cyclohexane (TBECH) and 2,3-dibromopropyl-2,4,6-tribromophenyl ether (DPTE) bind to the androgen receptor (AR). in vitro bioassays have shown that ...