dc.contributor.author | Yola, Bahar Bankoğlu | |
dc.contributor.author | Karaman, Ceren | |
dc.contributor.author | Özcan, Nermin | |
dc.contributor.author | Atar, Necip | |
dc.contributor.author | Polat, İlknur | |
dc.contributor.author | Yola, Mehmet Lütfi | |
dc.date.accessioned | 2022-11-15T08:18:03Z | |
dc.date.available | 2022-11-15T08:18:03Z | |
dc.date.issued | 2022 | en_US |
dc.identifier.citation | Yola, B.B., Karaman, C., Özcan, N., Atar, N., Polat, İ., Yola, M.L. (2022). Electrochemical Tau Protein Immunosensor Based on MnS/GO/PANI and Magnetite-incorporated Gold Nanoparticles. Electroanalysis, 34 (9), pp. 1519-1528.
https://doi.org/10.1002/elan.202200159 | en_US |
dc.identifier.uri | https://doi.org/10.1002/elan.202200159 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12508/2249 | |
dc.description.abstract | Herein, electrochemical tau protein immunosensor based on manganese sulfide nanoparticles/graphene oxide/polyaniline (MnS/GO/PANI) and magnetite-incorporated gold nanoparticles (AuNPs@Fe3O4) was constructed. After the modification of the glassy carbon electrode (GCE) with MnS/GO/PANI, the immobilization and conjugation of anti-Tau capture antibody and antigen Tau protein were successfully completed on MnS/GO/PANI/GCE, respectively. Then, the conjugation of anti-Tau secondary antibody was carried out to AuNPs@Fe3O4 as signal amplification via amino-gold affinity and the eventual immunosensor was accomplished by the distinctive interactions of electrode platform and signal amplification. Final immunosensor demonstrated the quantification limit (LOQ) of 1.0×10−13 M and the detection limit (LOD) of 1.0×10−14 M. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Wiley | en_US |
dc.relation.isversionof | 10.1002/elan.202200159 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Alzheimer's disease | en_US |
dc.subject | Detection | en_US |
dc.subject | Diagnosis | en_US |
dc.subject | Nanocomposite | en_US |
dc.subject | Voltammetry | en_US |
dc.subject.classification | Chemistry | |
dc.subject.classification | Electrochemistry | |
dc.subject.classification | Electrode | |
dc.subject.classification | Cobaltous Sulfide | |
dc.subject.classification | Electrode Materials | |
dc.subject.other | Au nanoparticles | |
dc.subject.other | Quantum dots | |
dc.subject.other | Iron-oxide | |
dc.subject.other | Supercapacitor | |
dc.subject.other | Carbon | |
dc.subject.other | Polyaniline | |
dc.subject.other | Biosensor | |
dc.subject.other | Electrode | |
dc.subject.other | Core | |
dc.subject.other | Nanocomposites | |
dc.title | Electrochemical Tau Protein Immunosensor Based on MnS/GO/PANI and Magnetite-incorporated Gold Nanoparticles | en_US |
dc.type | article | en_US |
dc.relation.journal | Electroanalysis | en_US |
dc.contributor.department | Mühendislik ve Doğa Bilimleri Fakültesi -- Biyomedikal Mühendisliği Bölümü | en_US |
dc.identifier.volume | 34 | en_US |
dc.identifier.issue | 9 | en_US |
dc.identifier.startpage | 1519 | en_US |
dc.identifier.endpage | 1528 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.contributor.isteauthor | Özcan, Nermin | |
dc.relation.index | Web of Science - Scopus | en_US |
dc.relation.index | Web of Science Core Collection - Science Citation Index Expanded | |